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You will have to consider the graph of how the reactants are finally transformed into the end products and what the amount of the activation energy used and released is.- When glucose reacts with oxygen to produce carbon dioxide and water, the role played by the catalytic enzymes is vital.- If the reaction takes place without the involvement of the enzymes the energy required for the reactants to reach the transition site is huge. The curve takes a sharp turn if drawn in the graph where the energy level is being calculated along the Y-axis and the coordinates for the reaction are placed in the X-axis.- But when enzymes are induced the reactants uses very less amount of the activation energy to reach the state of transition from where the generation of end products begins. drinking alcoholic beverages on zoloft zoloft and increasing dosages over time causing problem swallowing zoloft zoloft and vicodin smallest effective dose of zoloft